There is a lot of talk recently about GLP-1s, and lots of people use them to try and lose weight. While they are effective at decreasing appetite and leading to weight loss there are some things to consider first. An article from the National Strength and Conditioning Association’s Personal Trainer Quarterly titled “Preserving muscle in the era of GLP-1RA therapy – Practical strategies for exercise professionals” by Dalan Zydel discusses this topic in detail.

GLP-1s, or glucagon-like peptide-1 medications, have revolutionized weight loss and treatment for various conditions like type 2 diabetes, chronic kidney and liver conditions, sleep apnea, and the prevention of cardiovascular disease. Many people who use these medications lose up to 15-20% of their body weight. But with that weight loss, people lose lean muscle mass.  Research shows that with any calorie deficit, your body will shed weight from both fat and muscle.  

So, how can GLP-1 users prevent that? Let’s look at the steps you can take to prevent loss of muscle mass with Ozempic.